Abundant Tau Filaments and Nonapoptotic
2002-11-1 · By electron microscopy on tissue sections, abundant filaments made of hyperphosphorylated tau protein were detected throughout the brain and in the spinal cord. The majority of filaments resembled the half-twisted ribbons described previously in some cases of FTDP-17 ( Spillantini et al., 1998b ; Mirra et al., 1999 ; Rizzini et al., 2000 ; Neumann et al., 2001 ).
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